;Politics
- William "the Fonz" Wilson , Born 1990, Lochgilphead. "Better to burn out than to fade away!"
- William Wilson (Pennsylvania Politician) (''fl.'' 1910s), member of the United States House of Representatives from Pennsylvania 1815–1819
- William Wilson (Labour Politician) (born 1913), British Labour Member of Parliament 1964–1983
- William Wilson (Ohio Politician) , member of the House of Representatives from Ohio
- Bill Wilson (Scottish Politician) (born 1963 as William L. Wilson), Scottish nationalist
- William Bauchop Wilson (1862-1934), a U.S. (Scottish-born) labor leader and political figure.
- William Lyne Wilson , a United States Postmaster General
- William E. Wilson (1870-1948), a U.S. Representative from Indiana.
- William W. Wilson , member of the United States House of Representatives from Illinois
- William Wilber Wilfred Wilson , Canadian politician
- William Bauchop Wilson , the first US Secretary of Labor
- William Edward Wilson , member of the United States House of Representatives from Indiana
- William Henry Wilson , member of the United States House of Representatives from Pennsylvania
- William Wilson (1720-1796) , British Member of Parliament for Ilchester 1761–176
- William Wallace Wilson Alberta politician
;Sports
;Academics
;Others
- William Wilson (architect) (1641—1710), a British architect, builder and sculptor.
- William Wilson (soldier) (1847-1895), noted for being one of only nineteen individuals to receive the Medal of Honor twice.
- William (Amos) Wilson (c. 1762-1821), a figure in the folklore of southeastern and south-central Pennsylvania in the late Eighteenth and early Nineteenth Centuries; often referred to as The Pennsylvania Hermit.
- Bill Wilson (convict) , a man convicted of murdering two individuals who were later found alive
- Bill Wilson (pastor) , president and founder of Metro Ministries International
- Bill W. (b. William Griffith Wilson), co-founder of Alcoholics Anonymous
- Edward Adrian Wilson (''aka'' Bill Wilson), an Antarctic explorer
- William Wilson (soldier) , two time recipient of the Medal of Honor and member of the US Army's 4th Cavalry
- William (Amos) Wilson , often referred to as ''The Pennsylvania Hermit''
- William Hardy Wilson , a noted Australian architect, artist and author.
- William Wilson (architect) , an architect, builder and sculptor from Sutton Coldfield
- Sir William James Erasmus Wilson , a physician and surgeon
- William A. Wilson , first US Ambassador to the Holy See
- William C. Wilson , General Superintendent of the Church of the Nazarene
- William Othello Wilson , member of the US Army's 9th Cavalry, and recipient of the Medal of Honor
- William Scott Wilson (b. 1944), a premier author and translator of samurai literature.
- Willie Wilson (minister) , a Baptist minister and candidate for mayor of Washington, D.C.
;Fictional people
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