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Thorpe-Ziegler reaction

The Thorpe-Ziegler reaction or '''Ziegler method''' is the Intramolecular modification with a dinitrile as a reactant and a cyclic Ketone as the final reaction product after acidic hydrolysis. The reaction is conceptually related to the Dieckmann Condensation .


EXTERNAL LINKS

  • Thorpe-Ziegler reaction: ''4-Phosphorinanone, 1-phenyl-'' Organic Syntheses , Coll. Vol. 6, p.932 (1988); Vol. 53, p.98 (1973) Link



REFERENCES