can also refer to the following people:
- Sprague Cleghorn , former NHL hockey player
- L. Sprague De Camp , author
- A number of prominent people named Charles Sprague
- --- Charles Sprague (poet) , American poet
- --- Charles A. Sprague , former Governor of Oregon
- --- Charles E. Sprague , accountant, civil war hero, Volapükist, spelling reformer
- --- Charlie Sprague , an American baseball player
- Clifton Sprague , American admiral during World War II
- Ed Sprague (pitcher) , former Major League Baseball pitcher
- Ed Sprague (third Baseman) , former Major League Baseball third baseman, and son of the pitcher
- Erik Sprague , the self-styled Lizardman
- Frank J. Sprague , Father of Electric Traction
- Isaac Sprague , botanical illustrator
- Isaac W. Sprague , the ''Original Thin Man''
- Jack Sprague , the only 3-time NASCAR Craftsman Truck Series Champion
- Ken Sprague , political cartoonist
- Lucian Sprague , American railroad executive
- Peleg Sprague , politician from the state of Maine
- Peleg Sprague (New Hampshire) , politician from the state of New Hampshire
- Robert Lamison Sprague , American admiral during World War II
- Royal Sprague , 11th Chief Justice of the Supreme Court of California
- A number of prominent politicians named William Sprague
- --- William Sprague (1609–1675) , original American settler
- --- William Sprague (1799-1856) , a politician from Rhode Island, uncle of William Sprague (1830-1915)
- --- William Sprague (1809-1868) , a politician from Michigan
- --- William Sprague (1830-1915) , a politician from Rhode Island, nephew of William Sprague (1799-1856)
- --- William Peter Sprague (1827-1899), a politician from Ohio
- W.G.R. Sprague , London Theatre designer
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