Sorbitol Articles about
Sorbitol
 

Information About

Sorbitol




  ImageSize 100px
  IUPACName hexane-1,2,3,4,5,6-hexaol
  Section1 {{Chembox Identifiers
  CASNo 50-70-4
  PubChem 82170
  SMILES OCC(O)C(O)C(O)C(O)CO
  MeSHName Sorbitol


  Section2 {{Chembox Properties
  Formula <sub>6</sub><sub>14</sub><sub>6</sub>
  MolarMass 18217 g/mol
  Density 068 g/cm³
  MeltingPt 95 °C
  BoilingPt 296 °C


  Section3 {{Chembox Hazards




Sorbitol, also known as '''glucitol''', is a Sugar Alcohol the body metabolises slowly. It is obtained by Reduction of Glucose changing the Aldehyde group to an additional Hydroxyl group hence the name ''sugar alcohol''.


USE AS A SWEETENER

Sorbitol is used in various Cough Syrup s, and is usually listed under the inactive ingredients. Too much sorbitol (from 10 to 50g, or more for adults) can cause gastro-intestinal problems.

Sorbitol is a s (11 Kilojoule s) per Gram versus the average 4 calories (17 kJ) of Sugar and Starch , while retaining 60% of the Sweetness . As a food additive it has an E Number E420, categorized as a Sweetener , Emulsifier and Humectant , grouped under "Other natural agents".


USE AS A LAXATIVE

Sorbitol can be used as a non-stimulant Laxative by either in oral suspension or Suppository form. The drug works by drawing water into the Large Intestine , thereby stimulating bowel movements.http://www.cancer.org/docroot/CDG/content/CDG_sorbitol.asp Sorbitol has been determined safe to use in the elderly. Lederle FA: Epidemiology of constipation in elderly patients. Drug utilization and cost-containment strategies. Drugs and Ageing 6:465-469, 1995.


CLINICAL SIGNIFICANCE

Ingesting large amounts of sorbitol can lead to some abdominal pain, gas, and mild to severe Diarrhea . Sorbitol can also aggravate Irritable Bowel Syndrome and Fructose Malabsorption .

Even in the absence of dietary sorbitol, cells also produce sorbitol naturally. When too much sorbitol is produced inside Retinopathy and Neuropathy may be related to excess sorbitol in the cells of the Eye s and Nerve s. The source of this sorbitol in diabetics is excess Glucose , which goes through the Polyol Pathway .


OTHER USES

Sorbitol is often used in modern Cosmetics as a Humectant and Thickener . Some transparent Gel s can only be made with sorbitol as it has a Refractive Index sufficiently high for transparent formulations. It is also used as a Humectant in some Cigarette s.

Sorbitol is used as a Cryoprotectant additive (mixed with Sucrose and sodium poly Phosphate s) in the manufacture of Surimi , a highly refined, uncooked Fish paste most commonly produced from Alaska (or walleye) Pollock (''Theragra chalcogramma'').

Furthermore, Sorbitol, combined with Kayexalate , helps the body rid itself of excess Potassium ions in a Hyperkalemic state. The Kayexalate exchanges sodium ions for potassium ions in the bowel, while sorbitol helps to eliminate it.

Sorbitol when combined with potassium nitrate has found some success as an amateur solid rocket fuel. Richard Nakka's Experimental Rocketry Web Site

Sorbitol is identified as a potential key chemical intermediate ''Production of Liquid Hydrocarbons from Biomass '' Jürgen O. Metzger resources. Complete reduction of sorbitol opens the way to Alkane s such as Hexane which can be used as a Biofuel . Sorbitol itself provides much of the hydrogen required for the transformation.

:19 C6O6H14 → 13 C6H14 + 36 CO2 + 42 H2O

The above Chemical Reaction is Exothermic and 1.5 Mole of sorbitol generates 1 mole of Hexane . When hydrogen is co-fed, no Carbon Dioxide production takes place.


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