Information About

Phospholipids




is the major component of Lecithin . It is also a source for Choline in the synthesis of acetylcholine in cholinergic neurons g unit.]]

Phospholipids are a class of Lipids , and a major component of all Biological Membrane s, along with Glycolipid s, Cholesterol and Proteins . Understanding of the aggregation properties of these molecules is known as Lipid Polymorphism and forms part of current academic research.


COMPONENTS

They are built upon to a Nitrogen -containing Alcohol like Ethanolamine or an organic compound such as choline.


TYPES


Phosphoglycerides

In phosphoglycerides, g-unit the Carboxyl group of each fatty acid is esterified to the Hydroxyl groups on carbon-1 and carbon-2 of the glycerol molecule. The phosphate group is attached to carbon-3 by an ester link. This molecule, known as a Phosphatidate , is present in small quantities in membranes, but is also a precursor for the other phosphoglycerides.

In phosphoglyceride synthesis, Phosphatidate s must be activated first. Phospholipids can be formed from an activated Diacylglycerol or an activated alcohol.


  • In the synthesis of Phospatidyl Ethanolamine , the alcohol is phosphorylated by ATP first, and subsequently reacts with cytidine triphosphate (CTP) to form the activated alcohol (CDP-ethanolamine). The alcohol then reacts with a diacylglycerol to form the final product.




  Image:Phosphatidyl-Inositolpng "http://wwwinformationdelightinfo/information/entry/Phosphatidyl_inositol" class="copylinks">Phosphatidyl Inositol
  Image:Phosphatidyl-Serinepng "http://wwwinformationdelightinfo/information/entry/Phosphatidyl_serine" class="copylinks">Phosphatidyl Serine
  Image:Diphosphatidyl-Glycerolpng "http://wwwinformationdelightinfo/information/entry/Diphosphatidyl_glycerol" class="copylinks">Diphosphatidyl Glycerol (Cardiolipin)