Information AboutOpsonize |
| CATEGORIES ABOUT OPSONIN | |
| immune system | |
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MECHANISM Both the membrane of a phagocytising cell, as well as its target, have a negative charge (Zeta-potential), making it difficult for the two cells to come close together. During the process of ''opsonization'', Antigen s are bound by Antibody and/or Complement molecules. Phagocytic cells express receptors that bind opsonin molecules. With the antigen coated in these molecules, binding of the antigen to the phagocyte is greatly enhanced. Most phagocytic binding cannot occur without opsonization of the antigen. Furthermore, opsonization of the antigen and subsequent binding to an activated phagocyte will cause increased expression of complement receptors on neighboring phagocytes. EXAMPLES Examples of opsonin molecules include: The most important are IgG and C3b. SEE ALSO Antibody Opsonization . REFERENCES EXTERNAL LINKS |
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