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  HGNCid 11925
  Symbol TNFSF10
  EntrezGene 8743
  OMIM 603598
  RefSeq NM_003810
  UniProt P50591
  Chromosome 3
  Arm q
  Band 26


TNF-related apoptosis-inducing ligand (TRAIL), in the field of Cell Biology , is a Ligand molecule which induces the process of cell death called Apoptosis . It is a type II Transmembrane Protein with homology to other members of the Tumor Necrosis Factor family.

In humans, the gene that encodes for TRAIL is located at Chromosome 3q26.

TRAIL binds to the Death Receptor s, DR4 and DR5. The process of apoptosis is Caspase-8 -dependent.


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