- Mansfield, Arkansas , a city of 1,101
- Mansfield, Connecticut , a town of 24,228
- --- Mansfield Center, Connecticut , a census-designated place within the town of Mansfield
- Mansfield, Georgia , a city of 476
- Mansfield, Illinois , a village of 949
- Mansfield, Louisiana , a city of 5,496
- Mansfield, Massachusetts , a town of 22,414
- Mansfield, Missouri , a city of 1,349
- Mansfield, New York , a town of 800
- Mansfield, Ohio , a city of 50,615
- Mansfield, Pennsylvania , a borough of 3,463
- --- Mansfield University Of Pennsylvania
- Mansfield, Texas , a city of 51,300
- Mansfield, Washington , a town of 328
- Mansfield Plantation , South Carolina
- Mansfield Township, Burlington County, New Jersey , pop. 5090
- Mansfield Township, Warren County, New Jersey , pop. 6653
- Arabella Mansfield (1846–1911), first American female lawyer
- Charles John Moore Mansfield , (1760–1813), British Royal Navy captain
- Darrell Mansfield , American gospel/blues musician
- Edwin Mansfield , (1930–1997), economist, professor at the University of Pennsylvania
- Harvey Mansfield , Harvard government professor and conservative political commentator
- Jayne Mansfield (1933–1967), American actress and sex symbol
- Joseph K. Mansfield (1803–1862), Union army general in the American Civil War
- Katherine Mansfield (1888–1923), author
- Lord Mansfield ( William Murray, 1st Earl Of Mansfield ) (1705–1793), British jurist, creator of the decision that outlawed slavery in Great Britain
- Mark Mansfield , Director, Office of Public Affairs, CIA
- Mike Mansfield (1903–2001), Montana politician and statesman
- Peter Mansfield , British physicist and pioneer of MRI
- Wayne Mansfield , Australian-based marketer and convicted spammer
- The "Mansfield Decision" ( Somersett's Case ), a judicial decision (officially known as ''R. v. Knowles, ex parte Somersett'') ruling that there was no legal basis for slavery in England, effectively abolishing the practice of slavery in the country (although not in the British colonies)
- Maureen And Mike Mansfield Foundation , named after Mike Mansfield , dedicated to "advancing understanding and cooperation in U.S.-Asia relations"
- ''Mansfield Park'' (novel) , by Jane Austen
- Mansfield College , a college of Oxford University
- Mansfield, a character in the science fiction book '' The Humanoid Touch ''
- "Mansfield", a song by Elton John, on the album '' Songs From The West Coast ''
- Mansfield Dam , near Austin, Texas
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