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Information About

Malonic Acid




Malonic acid ( with structure C H 2( COOH )2. The Ion ised form of malonic acid, as well as its Ester s and Salt s, are known as '''malonates'''. For example, Diethyl Malonate is malonic acid's Ethyl Ester . The name originates from Latin ''malum'', meaning ''apple''.


BIOCHEMISTRY

The Calcium salt of malonic acid occurs in high concentrations in Beetroot .


ORGANIC SYNTHESIS

A classical preparation of malonic acid starts from generates the sodium Salt which is then reacted with Sodium Cyanide to the cyano acetic acid salt in a Nucleophilic Substitution . The Nitrile group can be Hydrolysed with Sodium Hydroxide to sodium malonate and acidification affords malonic acid.


ORGANIC REACTIONS

In a well known reaction malonic acid Condenses with Urea to Barbituric Acid . Malonic acid is frequently used as an Enolate in Knoevenagel Condensation s or condensed with Acetone to form Meldrum's Acid .


EXTERNAL LINKS


  • MSDS http://physchem.ox.ac.uk {Link without Title}

  • MSDS http://avogadro.chem.iastate.edu {Link without Title}

  • pH spectrum http://www.Theoprax-Research.com Disodium Malonate

  • pH spectrum http://www.Theoprax-Research.com [http://www.Theoprax-Research.com/MalonCu.html Malonic acid copper complex]



REFERENCES