- Ben W. Hooper (1870-1957), governor of Tennessee 1911-1915
- Carl Hooper (b. 1966) West Indian cricket player
- Chris Hooper (contemporary), Canadian musician
- Craig Hooper (contemporary), Australian musician
- Daniel Hooper (contemporary), British environmental protester
- Dirk Hooper (contemporary), American fetish photographer and fetish artist
- Ed Hooper (contemporary), American author, Tennessee Journalist and Historian
- Edward Hooper (contemporary), British journalist
- Ellen Sturgis Hooper (1812-1848), American Transcendentalist poet, daughter of William F. Sturgis
- Emma Hooper (contemporary), Canadian author and violist
- Harry Hooper (1887-1974), American baseball player
- Horace Everett Hooper (1859-1922), publisher of Encyclopædia Britannica
- Ibrahim Hooper , also known as Doug Hooper (contemporary), spokesman for the Council on American-Islamic Relations (CAIR)
- J. Robert Hooper , Maryland politician
- Joe R. Hooper (1938-1979), American Medal of Honor awardee
- Joseph L. Hooper (1877-1934), U.S. Representative from Michigan
- John Hooper (1495-1555), English churchman, Bishop of Gloucester and Worcester
- Johnson J. Hooper (c.1815-63) American humorist
- Lyndon Hooper (b. 1966), former professional Canadian soccer player
- Mike Hooper (contemporary), English footballer
- Nellee Hooper , (contemporary), British producer/remixer for popular/rock music groups
- Selden G. Hooper (1904-1976), United States Navy admiral convicted by court-martial
- Tobe Hooper (b. 1943), American television and film director in horror films
- Tom Hooper (1883-1960), Canadian professional ice hockey player
- Tom Hooper (contemporary), Canadian songwriter and musician
- William Hooper (1742-1790), signer of the United States Declaration of Independence
- Mr. Hooper , character on the children's TV show ''Sesame Street''
- Hooper X, character in Kevin Smith's 1997 film '' Chasing Amy ''
- Hooper, Colorado , town in Alamosa County, Colorado
- Hooper, Nebraska , town in Dodge County, Nebraska
- Hooper, Utah , place in Weber County, Utah
- Hooper Bay, Alaska , town in Alaska
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