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Hiv Ribosomal Frameshift Signal




The HIV Ribosomal frameshift signal is an RNA Element . HIV uses a system called -1 Ribosomal frameshifting to produce the required ratio of Gag and Gag-Pol polyproteins. The Stem-loop structure of the frameshift signal is thought to impede the ribosome and cause slippage in the 5' direction, this causes the -1 frameshift and Translation then continues in the new frame.1


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