Information About

Anisomycin




  IUPACName {Link without Title} pyrrolidin-3-yl] acetate
  OtherNames Flagecidin
  Section1 {{Chembox Identifiers
  CASNo 22862-76-6
  PubChem 31549
  SMILES CC(=O)OC1C(CNC1CC2=CC=C(C=C2)OC)O


  Section2 {{Chembox Properties
  Formula C<sub>14</sub>H<sub>19</sub>NO<sub>4</sub>
  MolarMass 265305


  Section3 {{Chembox Hazards






Anisomycin, also known as '''Flagecidin''' ( produced by '' Streptomyces Griseolus '' which inhibits Protein Synthesis . Partial Inhibition of DNA Synthesis occurs at anisomycin Concentration s that effect 95% inhibition of protein synthesis {Link without Title} . Anisomycin can activate Stress-activated Protein Kinase s, MAP Kinase and other Signal Transduction pathways.

Anisomycin is inactive against Bacteria .


PHARMACOLOGY

Anisomycin interferes with protein and DNA synthesis by inhibiting Peptidyl Transferase or the 80S Ribosome system.

Anisomycin is also mentioned as a potential Psychiatric Drug , as it may erase "short-range memory" {Link without Title} .

Injection of anisomycin into the Hippocampus has been proposed for selective removal of memories {Link without Title} .





REFERENCES

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SEE ALSO