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Zwitterion




, in its (1) normal (unionized) and (2) zwitterionic forms.]]
A zwitterion (from and usually have a high solubility in water and a poor solubility in most Organic Solvent s.

Ampholytes are molecules that contain both Acid ic and Basic groups (and are therefore Amphoteric ) and will exist as zwitterions at a certain PH . This pH is known as the molecule's Isoelectric Point . Ampholytic molecules make good Buffer Solution s — they resist change to the pH of a solution by selective ionization. In the presence of acids, they will accept the hydrogen ions, removing them from the solution. In the presence of Bases , they will donate hydrogen ions to the solution, again balancing the pH.

Typical examples of zwitterions are:




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