- Yazoo County, Mississippi
- Yazoo City, Mississippi
- Yazoo River , in the state of Mississippi
- Yazoo Delta Railroad
- Yazoo Lands , historic area in Mississippi and Alabama
- Yazoo Tribe , a Native American peoples who lived in Mississippi
- Yazoo Land Fraud
- Yazoo (band) , a 1980s English pop band renamed ''Yaz'' for the U.S. market
- Yazoo (drink) , a flavoured milk drink made by Campina
- Yazoo (language)
- Yazoo Brewing Company , a brewery in Nashville, Tennessee
- Yazoo/Kees (originally Yazoo Manufacturing Company), a maker of lawn mowers owned by Husqvarna
- Yazoo Records
- Yazoo Stream , a type of floodplain tributary
- Yazoo, a character from Final Fantasy VII Advent Children
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