- C.M.S. College , in Kottayam, Kerala, India, founded by the Church Missionary Society of England
- CMS Federal Training College , Australia, (St. Andrew's Hall) adjacent to Ridley College (University of Melbourne)
- Chicago Medical School , part of Rosalind Franklin University in North Chicago, Illinois
- City Montessori School , a private undergraduate school in Lucknow, India, founded by Dr. Maria Montessori of Italy
- Claremont-Mudd-Scripps Athletics , The combined athletics program which serves Claremont McKenna College , Harvey Mudd College , and Scripps College . Located in Claremont, California.
- Calexico Mission School , a private Adventist school in Calexico, California, USA
- Carmenita Middle School , a public middle school in Cerritos, California.
- Carol Morgan School, a high end private K-12 school in Santo Domingo, Dominican Republic .
- Centennial Middle School , a public middle school in Snohomish, Washington .
- Charlotte-Mecklenburg Schools , school district in North Carolina, USA
- Circleville Middle School , a public middle school in New York.
- Clearfield Middle School , a public middle school in Clearfield, Pennsylvania.
- Community Middle School , a public middle school in Plainsboro, New Jersey
- Cresthill Middle School, a public middle school in Hylands Ranch, Colorado
- Cupertino Middle School , a public middle school in California.
- Cabin Management System , digital control of an aircraft's in-flight entertainment
- Certified Master Safecracker , as awarded by the National Safeman's Organization
- Changeable-message Sign , a variable road sign
- '' The Chicago Manual Of Style '', a guide to American English publication style
- Chronic Mountain Sickness , also known as Monge's disease, a disease caused by living a long time at high altitude
- Constant Maturity Swap , a type of financial swap
- Critical Management Studies , a left wing approach to management, business and organisation
- CMS Light Alloy Wheels , light alloy wheel manufacturer in Turkey
- Cms (angel) , a minor angel in Enochian
- ''Common Message Switch'', a financial information exchange protocol which some exchanges use in place of the more standard FIX Protocol
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