- Titan (mythology) , a class of deities who preceded the Olympians in Greek mythology
- Helios , Greek sun-deity sometimes referred to as "Titan"
- Titan (Imperial Guard) , a member of the Shi'ar Imperial Guards in the Marvel Universe
- '' Titan A.E. '', an animated sci-fi space adventure movie
- ''Titan'' (Stephen Baxter) , a science fiction novel by Stephen Baxter
- Titan (John Varley) , the first book in the Gaea Trilogy, by science fiction author John Varley
- Titans (comics) , also known as The ''Teen Titans'', a group of DC Comics superheroes
- Titan (Comics Greatest World) , a superhero turned supervillain in the Dark Horse Comics imprint Comics' Greatest World
- Titan (Dune) , a group of immortal cymeks in Brian Herbert's and Kevin J. Anderson's book ''The Butlerian Jihad''
- USS ''Titan'' (Star Trek) , a Starfleet ship in Star Trek
- ''Titans'' (TV Series) , starring Casper Van Dien and Yasmine Bleeth
- ''Titan'' (Ben Bova) , a novel in the " Grand Tour " series
- Titans, an elite counter-insurgency group in '' Mobile Suit Zeta Gundam ''
- Hades God Titan of the Infershia Pantheon from ''Mahou Sentai Magiranger''
- Two dinosaurs called the Titans that were going to be in the movie Terror Of Mechagodzilla , but they didn't make it into the movie.
- Titan (Planets Of Warhammer 40,000) ''Titan'' the legendary homeworld of the Grey Knight Space Marine chapter.
- ''Titan'' (game) , a fantasy war board game
- Titan (world) , the Fighting Fantasy Game Books world that was created by Steve Jackson and Ian Livingstone
- Titan (Dungeons & Dragons) , a Dungeons & Dragons race of Outsiders
- Titan (Warhammer 40,000) , massive walking war-engines armed with powerful weapons
- Titans (Warcraft) , a race of beings that shape worlds in order to encourage the development of sentient life
- Titan (game Engine) , a game engine developed by Stainless Steel Studios
- ''Titan'' (1989 Computer Game) , an obscure Arkanoid/Breakout-clone made by Titus
- Titan (Final Fantasy Character) , a summoned beast in the ''Final Fantasy'' series
- '''', an expansion pack to the game ''Age of Mythology''
- The ''titan reactor'' on explorer-class science vessels in the science-fiction series '' StarCraft ''.
- Titan, the strongest upgraded unit of the Tower town in the '' Heroes Of Might And Magic '' series
- Titans, the largest ship class in '' EVE Online ''
- Titans, huge transport and assault vehicles in '' Battlefield 2142 ''
- Titan, GDI's Medium Battle Mechanized Walker in ''''
- Acadie-Bathurst Titan , hockey team in the Quebec Major Junior Hockey League
- Gold Coast Titans , Australian rugby league team
- Titans Cricket Team , the Nashua Titans, a South African cricket team based in Centurion and Benoni
- Tennessee Titans , American football team in the National Football League
- New York Titans , former name of the New York Jets, an American football team
- New York Titans (NLL) , a team in the National Lacrosse League
- California State University, Fullerton 's athletic teams, nicknamed "The Titans"
- The St. John's Jesuit High School And Academy Titans, in Toledo, Ohio
- The Syracuse High School Titan's located in Syracuse, Utah
- Wichita South High School whose mascot is the Titan.
- Chevrolet Titan , a cabover tractor-trailer truck made by Chevrolet from 1968-1988
- Leyland Titan (B15) and Leyland Titan , Leyland's double-deck buses
- Nissan Titan , a full-size pickup truck for the North American market
- Titan Aircraft , a company specializing in ultralight aircraft kits
- Titan Airways , a charter airline
- Titan Books , a UK publisher of graphic novels
- --- Titan Magazines
- Titan Cement , an international cement company.
- Titan Corporation , a private military contractor
- Titan Industries , an Indian watchmaker
- TITAN2D , software application; a numerical code for simulating granular avalanches.
- Titan (roller Coaster) , at Six Flags Over Texas, produced by Giovanola
- Titan (computer) , prototype Atlas 2 computer developed in the early 1960s
- Titan, a South Devon Railway Gorgon Class 4-4-0ST steam locomotive
- Terex Titan 33-19, largest dump truck in the world, one-of-a-kind, parked in Sparwood, BC, Canada
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