may refer to:
- Macon State College
- Mail Services Center
- Manly Selective Campus , a selective high school in New South Wales, Australia
- Manned Spacecraft Center , the former name of today's Johnson Space Center
- Marianites Of Holy Cross
- Marine Stewardship Council
- Marksmen Snipers Coalition, an online gaming community that is invite only.
- Math, Science, and Computers program at Winston Churchill High School (Wayne County, Michigan)
- Multi-Service Center , a Building at Chesapeake College
- Masters Of Science , usually MSc or M.Sc.
- USB Mass Storage Device Class
- Mathematics Subject Classification
- Mediated Settlement Conference, A Type Of Alternative Dispute Resolution Or ADR
- Medical Service Corps , a part of the medical services of various nations' armed forces
- Mediterranean Shipping Company S.A. .
- ---Ships operated by Mediterranean Shipping Company, including
-- MSC Armonia
-- MSC Musica
-- MSC Napoli
-- MSC Opera
-- MSC Pamela
- Meritorious Service Cross , a Canadian decoration of post-nominal letters
- Mesenchymal Stem Cell
- Message Sequence Chart
- Meteorological Services Of Canada
- Metropolitan Special Constabulary
- Michigan State College , the archaic name of the now Michigan State University
- Microelectronics Support Centre
- Microsoft Corporation
- Mid-Size Communities
- Mid-South Conference
- MIDI Show Control
- Military Sealift Command
- Military Staff Committee
- Missionaries Of The Sacred Heart
- Mobile Switching Center , a part of a GSM , TDMA , CDMA , or Cellular network
- Modern Standard Chinese
- Most Significant Change monitoring
- Mount Saint Charles Academy
- MSC Industrial Direct Co., Inc (formerly known as Manhattan Supply Company)
- MSC Italian Cruises
- MSC Software
- Multimedia Super Corridor , in Malaysia
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