- Charles Clerke (1741–1779), British naval officer and explorer.
- Ellen Mary Clerke (1840–1906), Irish journalist, poet and writer on astronomy.
- Agnes Mary Clerke (1842–1907), Irish astronomer and science writer.
- Clerke , a lunar crater named after Agnes Mary Clerke.
- The Clerke Rocks , a group of small rocky islands in the South Atlantic, named after Charles Clerke.
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