Information About

Cyp2c19




  HGNCid 2621
  Symbol CYP2C19
  AltSymbols CYP2C
  EntrezGene 1557
  OMIM 124020
  RefSeq NM_000769
  UniProt P33261
  Chromosome 10
  Arm q
  Band 24


Cytochrome P450 2C19 (abbreviated '''CYP2C19'''), a member of the Cytochrome P450 mixed-function oxidase system, is involved in the metabolism of Xenobiotic s in the body. It is involved in the metabolism of several
important groups of drugs including many Proton Pump Inhibitor s and Antiepileptic s.

Genetic Polymorphism exists for CYP2C19 expression, with approximately 3–5% of Caucasian and 15–20% of Asian populations being Poor Metaboliser s with no CYP2C19 function.


CYP2C19 LIGANDS



SEE ALSO