- Cal-Animage Alpha , one of the oldest anime clubs in the United States
- Canadian Archaeological Association , an organization dedicated to promote and increase the dissemination of archaeological knowledge in Canada
- Canadian Automobile Association , non-profit federation of nine clubs across Canada, providing roadside assistance services
- Canadian Avalanche Association , a non-profit organization that promotes avalanche awareness and safety
- Case Alumni Association , oldest independent alumni organization in the United States
- Center For Academic Advancement , a part of the Johns Hopkins University Center for Talented Youth
- Center For American Archeology , in Kampsville, Illinois, an independent non-profit 501(c)3 research and education institution
- Cerebral Amyloid Angiopathy , a form of angiopathy in which the amyloid protein associated with Alzheimer's disease deposits in the walls of the blood vessels of the brain
- China Academy Of Art , the highest university of art in China which founded in 1928
- China Automobile Association , China’s largest roadside assistance provider
- Civil Aviation Authority , name for the national body governing civil aviation in a number of countries
- Clean Air Act , a number of pieces of legislation relating to the reduction of smog and atmospheric pollution
- College Art Association , an organization that supports all practitioners and interpreters of visual art and culture, including artists and scholars, who join together to cultivate the ongoing understanding of art as a fundamental form of human expression. Representing its members' professional needs, CAA is committed to the highest professional and ethical standards of scholarship, creativity, connoisseurship, criticism, and teaching
- Colonial Athletic Association , an NCAA Division I college athletic conference whose members are located in East Coast states from Massachusetts to Georgia
- Computational Aeroacoustics , direct simulation of acoustic fields generated by flows and of the interaction of acoustic fields with flows
- Confederation Of African Athletics
- Contemporary Applied Arts , a registered charity set up to champion and promote British craft
- Continental Airlines Arena , an arena in East Rutherford, New Jersey
- Creative Artists Agency , American show business agency
- Cyprus Automobile Association non-profit organisation, providing roadside assistance services
- CAA is the ICAO Airline Designator for Atlantic Southeast Airlines in the United States
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