Year ( MDXLIII ) was a Common Year Starting On Monday (link will display the full calendar) of the Julian Calendar .
: Nicolaus Copernicus .]]
- January 18 - (baptized) - Alfonso Ferrabosco , Italian composer (died 1588 )
- January 31 - Tokugawa Ieyasu , Japanese shogun (died 1616 )
- February 15 - Charles III, Duke Of Lorraine (died 1608 )
- February 16 - Kano Eitoku , Japanese painter (died 1590 )
- April 1 - François De Bonne, Duc De Lesdiguières , Constable of France (died 1626 )
- September 14 - Claudio Aquaviva , Italian Jesuit (died 1615 )
- ''date unknown''
- --- Thomas Deloney , English novelist and balladeer (died 1600 )
- --- Domenico Fontana , Italian architect (died 1607 )
- --- Sonam Gyatso, 3rd Dalai Lama , first Dalai Lama (died 1588 )
- --- François Pithou , French lawyer and author (died 1621 )
- --- Hayyim Ben Joseph Vital , rabbi and mystic (died 1620 )
- --- Chen Lin , general of Ming Dynasty
- ''probable''
- --- Giovanni Maria Nanino , Italian composer (died 1607 )
- --- Federico Zuccari , Italian painter (died 1609 )
- January 2 - Francesco Canova Da Milano , Italian composer (born 1497 )
- January 3 - Juan Rodríguez Cabrillo , Portuguese explorer (born 1499 )
- January 9 - Guillaume Du Bellay , French diplomat and general (b. 1491 )
- February 21 - Ahmad Ibn Ibrihim Al-Ghazi , Imam of Adal (killed in battle) (born c 1506 )
- May 24 - Nicolaus Copernicus , mathematician and astronomer (born 1473 )
- July 19 - Lady Mary Boleyn , mistress of Kings Francis I Of France and Henry VIII Of England (born 1500 )
- September 20 - Thomas Manners, 1st Earl Of Rutland (born 1492 )
- November 29 - Hans Holbein The Younger , German artist, active in England
- December 27
- --- George, Margrave Of Brandenburg-Ansbach (born 1484 )
- --- Francesco Spiera , Protestant Italian jurist (born 1502 )
- ''date unknown''
- --- Polidoro Caldara Da Caravaggio , Italian painter (born 1492 )
- --- Baccio D'Agnolo , Florentine woodcarver (born 1460 )
- ''probable''
- --- Sebastian Franck , German freethinker (born 1515 )
- --- Margaret Lee , sister of poet Thomas Wyatt (born 1506 )
- --- Sultan Quli Qutb Mulk , founder of the Qutb Shahi dynasty of Golconda
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