Year ( MDXLI ) was a Common Year Starting On Saturday (link will display the full calendar) of the Julian Calendar .
: Voyage of Francis Xavier .]]
: De Soto at Mississippi River .]]
: Golden Gate .]]
- January 26 - Florent Chrestien , French writer (d. 1596 )
- March 25 - Francesco I De' Medici, Grand Duke Of Tuscany (died 1587 )
- April 8 - Michele Mercati , Italian physician and gardener (died 1593 )
- ''date unknown''
- --- Pierre Charron , French philosopher (died 1603 )
- --- Walter Devereux, 1st Earl Of Essex , English nobleman (died 1576 )
- --- painter, sculptor and architect (died 1614 )
- --- Hatano Hideharu , Japanese samurai (died 1579 )
- --- Mizuno Tadashige , Japanese nobleman (died 1600 )
- --- Guðbrandur Þorláksson , mathematician (died 1627 )
- --- Hattori Hanzō , Ninja who served under Tokugawa Ieyasu (died 1596 )
- April - Jerzy Radziwiłł , Polish nobleman (born 1480 )
- May 27 - Margaret Pole, 8th Countess Of Salisbury (executed) (born 1473 )
- June 26 - Francisco Pizarro , Spanish conquistador (born c class="copylinks">Born C[[1475 ])
- July 4 - Pedro De Alvarado , Spanish conquistador (born 1495 )
- August 1 - Simon Grynaeus , German scholar and theologian (born 1493 )
- September 24 - Paracelsus , Swiss alchemist (b. 1493 )
- November - Wolfgang Fabricius Capito , German reformer (born 1478 )
- November 24 - Margaret Tudor , queen of James IV Of Scotland (born 1489 )
- December 10 - Thomas Culpeper , English courtier (executed)
- December 24 - Andreas Karlstadt , Christian theologian and reformer (born 1486 )
- ''date unknown''
- --- Jean Clouet , French miniature painter
- --- Giovanni Guidiccioni , Italian poet (born 1480 )
- --- Gendun Gyatso, 2nd Dalai Lama (born 1474 )
- --- Amago Tsunehisa , Japanese warlord
- --- Juan De Valdés , Spanish religious writer (born 1500 )
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