Year was a Common Year Starting On Wednesday (link will display the full calendar) of the Julian Calendar ).
- January 12 - Henry III Of Nassau-Breda , Baron of Breda (died 1538 )
- February 14 - Zahir Al-Din Mohammed Babur Shah , founder of the Moghul dynasty (died 1530 )
- March 6 - Francesco Guicciardini , Italian historian (died 1540 )
- April 6 - Rafael , Italian painter and architect (died 1520 )
- October 16 - Gasparo Contarini , Italian diplomat and cardinal (died 1542 )
- November 10 - Martin Luther , German monk and Protestant reformer (died 1546 )
- December 3 - Nicolaus Von Amsdorf , German Protestant reformer (died 1565 )
- ''date unknown''
- --- Cacamatzin , Aztec ruler (died 1520 )
- --- Jacquet Of Mantua , French composer (died 1559 )
- --- Chen Chun , Chinese painter (died 1544 )
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