Born in St. Paul, Minnesota , he was a very prolific film and TV actor, having worked on over 140 films. He started in show business working in Vaudeville , then moved on to Broadway . His film career began in 1926 and spanned the decades up to the 1970s. His most famous TV role was in '' My Three Sons '' from 1965 to 1972, playing Uncle Charley and replacing William Frawley , whose health had made procuring insurance impossible.