Vasodilation

Vasomotor refers to the muscles and nerves controlling the process of vasodilation.

A vasodilator is a substance that causes vasodilation. Several vasodilators are used as Drugs which may, for example, allow blood to flow more easily around a Clot .

Flushing may be a physiological response to vasodilators.

NATURAL VASODILATORS AND DRUGS THAT EXPLOIT THEM

Absence of high levels of Environmental Noise

Adenosine

--- Adenocard - this is primarily used as an anti- Arrhythmic .

Adrenaline and Noradrenaline vasodilate arterioles of the Skeletal Muscle s. (By acting on beta-2 Adrenergic Receptor s.) These chemicals cause Vasoconstriction elsewhere.

--- Alpha Blocker s (block the constricting effect of adrenaline).

Atrial Natriuretic Peptide (ANP) - a weak vasodilator.

Bradykinin

Histamine

--- Complement proteins C3a, C4a and C5a work by triggering histamine release from Mast Cell s and Basophil Granulocyte s.

L- Arginine

Niacin (aka Nicotinic Acid )

Nitric Oxide

--- Glyceryl Trinitrate (commonly known as Nitroglycerin )

--- Isosorbide Mononitrate & Isosorbide Dinitrate

--- Pentaerythritol Tetranitrate (PETN)

--- Sodium Nitroprusside

--- PDE5 Inhibitor s: these agents indirectly increase the effects of nitric oxide

-- Sildenafil

-- Tadalafil

-- Vardenafil

Platelet Activating Factor (PAF)

Prostacyclin (PGI₂) as well as other Prostaglandin s.

Tetrahydrocannabinol (THC) - the major active chemical in Marijuana . Its mild vasodilating effects redden the eyes of Cannabis smokers.

Papaverine an alkaloid found in the opium poppy Papaver Somniferum

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Vasodilation