Information About

Tryptamine






Tryptamine (3-(2- Amino Ethyl ) Indole ) is a Monoamine Compound that is widespread in nature. Biosynthesis generally proceeds from the Amino Acid Tryptophan , with tryptamine in turn acting as a precursor for other compounds including Indole , Beta-carboline and Ergoline Alkaloids and Auxins .

Substitutions to the tryptamine molecule give rise to a group of compounds collectively known as '''tryptamines'''. The most well-known tryptamines are Serotonin , an important Neurotransmitter , and Melatonin , a Hormone involved in regulating the sleep-wake cycle. Tryptamine Alkaloids found in Fungi , Plants and Animal s are commonly used by Humans for their Psychotropic effects. Prominent examples include Psilocybin (from " Magic Mushroom s") and DMT (from numerous plant sources, e.g. Chacruna , often used in Ayahuasca brews). Many Synthetic tryptamines have also been made, including the Migraine Drug Sumatriptan and its relatives. The table below lists some commonly encountered substituted tryptamines.

The tryptamine backbone can also be identified as part of the structure of some
more complex compounds, for example: Ergoline alkaloids like LSD , Ibogaine and Yohimbine .

A thorough investigation of dozens of tryptamine compounds was published by Ann and Alexander Shulgin under the title TiHKAL .





SEE ALSO




EXTERNAL LINKS