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Information About

Signal-recognition Particle




A signal-recognition particle or '''SRP''' is a cytosolic particle that transiently binds:
#To the Endoplasmic Reticulum (ER) Signal Sequence in a Nascent protein
#To the large ribosomal unit
#To the SRP Receptor

SRP and its receptor initiate the transfer of the Nascent chain across the ER membrane. Once the chain reaches the Translocon , SRP and its receptor dislocate.


COMPONENTS

  • P9

  • P14

  • P19

  • P54

  • P68

  • P72

  • SRP RNA