Information About

Rac1




Rac1 belongs to the Rho family of GTPase s. It is a Pleiotropic regulator of many cellular processes, including the cell cycle, cell-cell adhesion, Motility (through the actin network), and of Epithelial Differentiation (proposed to be necessary for maintaining epidermal stem cells).

See: Benitah SA et al., "Stem cell depletion through epidermal deletion of Rac1" ''Science'' 2005 Aug 5; 309(5736):933-935