Information AboutPunicalagins |
| CATEGORIES ABOUT PUNICALAGINS | |
| nutrition | |
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Punicalagins are Tannins , large polyphenol compound which are isomers of 2,3-(S)-hexahydroxydiphenoyl-4,6-(S,S)-gallagyl-D-glucose, hydrolysable tannins with a molecular weight of 1084. Punicalagins are the largest molecule found intact in rat plasma after oral ingestion (Biomed. Pharmacother. 2002, 56, 276-82) and were found to show no toxic effects in rats who were given a 6% diet of punicalagins for 37 days. (J. Agric. Food Chem. 2003, 51, 3493-3501). Punicalagins are also found to be the major component responsible for Pomegranate juice's antioxidant and health benefits (J Agric Food Chem 2000 48 (10) 4581-89). A few Dietary Supplements and nutritional ingredients are available that contain extracts of whole pomegranate and/or are standardized to punicalagins, the marker compound of pomegranate. Extracts of pomegranate are also 'Generally Recognized As Safe' (GRAS) by the United States. It has been recommended to look for pomegranate ingredients that mimic the polyphenol ratio of the fruit, as potent synergistic effects have been observed in 'natural spectrum' extracts, especially pomegranate concentrate normalized to punicalagins (J Nutr Biochemistry 2005 (16) 360-367). |
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