- A Greek word (also spelled ''Psykhē'' or ''Psukhē'') which means either " Soul " or " Butterfly ". Psycho- , and psyche- are common English prefixes for mind or soul-related concepts.
- In late Greek art and literature, a goddess who is the personification of the soul; she is primarily known for her role in the story of Cupid And Psyche , best attested in Apuleius ' novel '' The Golden Ass ''.
- 16 Psyche , an asteroid
- Psychidae , or Bagworms, a family of Lepidoptera
- Psyche (band) , a canadian synthpop/darkwave duo
- ''Psyche'', an album by British band Ant And Dec
- A code name for Red Hat Linux 8.0.
- Psyche (journal) , an academic journal devoted to the interdisciplinary study of consciousness.
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