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Penicillin Binding Protein




Their name is derived from the observation that they bind radioactive penicillin and can thus be detected by Autoradiography of Electrophoresis gels. Further, names usually include a number which relates to its molecular weight.

The action of the β-lactam Antibiotics (which includes penicillin) involves binding these proteins, thus preventing the formation of peptidoglycans which are essential components of the cell wall.