| Oxygen-haemoglobin Dissociation Curve |
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Information AboutOxygen-haemoglobin Dissociation Curve |
| CATEGORIES ABOUT OXYGEN-HAEMOGLOBIN DISSOCIATION CURVE | |
| chemical pathology | |
| hematology | |
| oxygen | |
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The shape of the oxygen-haemoglobin dissociation curve is a phenomenon resulting from the interaction of bound oxygen molecules with incoming molecules. The binding of the first molecule is difficult. However, this facilitates the binding of the second and third molecules, and it is only when the fourth molecule is to be bound that the difficulty increases, partly as a result of crowding of the haemoglobin molecule, partly as a natural tendency of oxygen to dissociate. ''Example of an Oxygen-haemoglobin dissociation curve'' Left shift of the curve is a sign of haemoglobins increased affinity for oxygen (eg. at the lungs). Similaryly, right shift shows decreased affinity, as would appear on an increase in body temperature, hydrogen ion, 2,3-bisphosphoglycerate or carbon dioxide concentration (the Bohr efect) |
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