| Nuclear Localization Signal |
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Information AboutNuclear Localization Signal |
| CATEGORIES ABOUT NUCLEAR LOCALIZATION SIGNAL | |
| cell biology | |
| cell signaling | |
| molecular genetics | |
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Genetically the NLS results from transcription of a nuclear localizing sequence. Cellular processes and protein function may be studied by adding a known NLS sequence to a gene, confining the Chimeric Protein product to the Nucleus . An NLS is the opposite of a Nuclear Export Signal , which confines proteins to the Cytosolic face of the Nuclear Membrane . Typically the NLS will have a sequence (NH2)-Pro-Pro-Lys-Lys-Lys-Arg-Lys-Val-(COOH). |
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