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Metal Acetylide




Acetylide ions are very useful in Organic Chemistry reactions in combining carbon chains, particularly Addition and Substitution Reaction s. One type of reaction displayed by acetylides are Addition Reaction s with Ketone s to form Tertiary Alcohol s. In the reaction in ''scheme 1'' the alkyne proton of ''ethyl propiolate'' is deprotonated by N-butyllithium at -78 °C to form lithium ethyl propiolate to which Cyclopentanone is added forming a Lithium Alkoxy . Acetic Acid is added to remove lithium and liberate the free alcohol .


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