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Malonyl-coa
 

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Malonyl-coa





Malonyl CoA is utilised in fatty acid biosynthesis by the enzyme Malonyl coenzyme A: Acyl Carrier Protein transacylase (MCAT). MCAT serves to transfer malonate from malonyl CoA to the terminal thiol of ''holo'' acyl carrier protein (ACP).

Controversy still exists whether MCAT is also involved in bacterial polyketide biosynthesis however there is evidence that the Acyl Carrier Protein from a variety of bacterial polyketide synthases is capable of self malonylation in the presence of malonyl CoA.