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Polymer s and molecules which structurally include polymers. {Link without Title} Many examples come from biology and in particular Biochemistry . These include Protein s, Starches , Lipid s and Nucleic Acid s (such as DNA ), which are sometimes called "biomacromolecules" or Biopolymer s. Synthetic examples include Plastic s. The integral Domain s of Crystal s and Metal s, while composed of very large numbers of atoms joined by molecule-like bonds, are rarely referred to as "macromolecules." The term macromolecule is also sometimes used to refer to aggregates of two or more macromolecules held together by Intermolecular Force s rather than by Chemical "bonds". This usage is common in particular when the individual macromolecules involved aggregate or "assemble" spontaneously and rarely exist in isolation. Such an aggregate is more properly called a '''macromolecular complex'''. In such a context, individual macromolecules are often referred to as subunits (see e.g. Protein Subunit ). Substances that are composed of macromolecules often have unusual physical properties. The properties of Liquid Crystal s and such Elastomer s as Rubber are examples. Although too small to see, individual pieces of DNA in solution can be broken in two simply by suctioning the solution through an ordinary straw. This is not true of smaller molecules. The 1964 edition of Linus Pauling 's ''College Chemistry'' asserted that DNA in nature is never longer than about 5000 Base Pair s. This is because biochemists were inadvertently and with perfect consistency breaking their samples into pieces. In fact, the DNA of Chromosome s can be tens of millions of base pairs long. Another common macromolecular property that does not characterize smaller molecules is the need for assistance in dissolving into solution. Many require Salt s or particular Ion s to dissolve in water. Proteins will Denature if the solute concentration of their solution is too high or too low. According to IUPAC recommendations the term macromolecule is reserved for an individual molecule, and the term '''polymer''' is used as to denote a substance composed of macromolecules. '''Polymer''' may also be employed unambiguously as an adjective, according to accepted usage, e.g. ''polymer blend'', ''polymer molecule''. {Link without Title} EXTERNAL LINKS
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