| Linda B. Buck |
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In their landmark paper published in 1991 , Buck and Axel Cloned olfactory receptors, showing that they belong to the family of G Protein-coupled Receptor s. By analyzing Rat DNA , they estimated that there were approximately one thousand different Gene s for olfactory receptors in the Mammalian Genome . This research opened the door to the Genetic and Molecular analysis of the mechanisms of Olfaction . Born in Seattle, Washington , Buck received her B.S. in Psychology and Microbiology in 1975 from the University Of Washington , Seattle and her Ph.D. in Immunology in 1980 from the University Of Texas Southwestern Medical Center At Dallas . She did her Post-doctoral work at Columbia University under Axel. Her primary research interest is on how Pheremone s and Odor s are detected in the nose and interpreted in the brain. She is also studying the mechanisms underlying aging and the lifespan of '' C. Elegans ''. She is a Full Member of the Basic Sciences Division at Fred Hutchinson Cancer Research Center , an Affiliate Professor of Physiology and Biophysics at the University Of Washington, Seattle and an Investigator of the Howard Hughes Medical Institute . She was inducted into the National Academy Of Sciences in 2004 . REFERENCES
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