is a condition caused by the buildup of
Lactic Acid in the body. It leads to acidification of the blood (
Acidosis ), and is considered a distinct form of
Metabolic Acidosis .
The cells produce lactic acid when they use
Glucose for energy in the absence of adequate
Oxygen . If too much lactic acid stays in the body, the balance tips and the person begins to feel ill. The signs of lactic acidosis are deep and rapid breathing, vomiting, and abdominal pain. Lactic acidosis may be caused by
Diabetic Ketoacidosis or
Liver or
Kidney disease, as well as some forms of medication (most notably
Metformin ).
The ''Cohen-Woods classification'' (1976) categorises causes of lactic acidosis as follows:
- Type A: Decreased perfusion or oxygenation
- Type B:
- --- B1: Underlying diseases (sometimes causing type A)
- --- B2: Medication or intoxication
- --- B3: Inborn Error Of Metabolism
Metabolic Acidosis
