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Itch




  Name Pruritus
  ICD10
  ICD9
  ICDO
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  OMIM
  MedlinePlus 003217
  EMedicineSubj
  EMedicineTopic
  DiseasesDB 25363


An itch ( felt on an area of Skin that makes a person or animal want to Scratch it. It is a distressing symptom that can cause discomfort. Scratching may cause breaks in the skin that may result in infection. Pruritus can be related to anything from dry skin to undiagnosed cancer.


MECHANISM

The central chemical in itch is Histamine , a molecule released by Mast Cell s in the skin. Histamine is the chemical that causes the itch and reddening when bitten by insects. It binds to local nerve endings on specific Receptors .

Itch from cutaneous ( Skin -related) stimuli, such as movement of small Hair s on the body, is transmitted along the same pathway as Pain . Itch caused by Histamine is transmitted to the Brain by a different neural pathway, described in 2001 by Andrew ''et al''. As with pain, histamine-induced itch travels via the Spinothalamic Tract , but in fibres specific for itch.


CAUSES

The feeling of itchiness can be caused by movement of hairs or release of a chemical ( Histamine ) from cells under the skin. Itchiness is regarded as protective, as it helps creatures remove parasites that land on them.

Other causes for itching can be:


TREATMENT

Itching can be treated directly with an Antipruritic or the use of a Back Scratcher . Ice can also be helpful.


REFERENCES

  • Andrew D, Craig AD (2001). Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch. ''Nature Neuroscience'' Jan;4(1):9-10.

  • National Cancer Institute (2003) "Pruritus" Retrieved Aug. 22, 2005.



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