, or '''cis-1,2,3,5-trans-4,6-cyclohexanehexol''', is a cyclic polyalcohol that plays an important role as a
Second Messenger in a
Cell , in the form of
Inositol Phosphate s. It is found in many foods, namely
Cereal s with high
Bran content.
It is classified as a member of the
Vitamin B complex, though it is not considered a
Vitamin per se, since the human body can synthesize it.
The chemical formula of inositol is
6126. There are 9
Isomer s, all of which are called inositol.
The inositol ring is in the
Chair Conformation . The 1
st, 3
rd, 4
th, 5
th and 6
th Hydroxyl s are positioned
Equatorial ly to the plane of the ring, while the 2
nd hydroxyl group is positioned
Axial ly to the plane of the ring.
Inositol is synthesized from
G6P in two steps. First G6P is
Isomer ized by
INYNA1 to ''myo''-inositol 1-phosphate, which is then dephosphorylated by
IMPA1 to yield inositol.
It is involved in :
It is also involved in the breakdown of
Fat s and reducing blood
Cholesterol .
Inositol phosphates are involved in
Gene Expression (Wu 2003 and OShea 2003 both in Science).
Some preliminary results of studies on inositol supplements show promising results for people suffering from problems such as
Bulimia ,
Panic Disorder and
Bipolar Depression .
Inositol has been found in double-blind studies to be an effective treatment for
Obsessive-compulsive Disorder (OCD) . It is equal in effectiveness to
SSRIs and is virtually free from side effects
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- Inositol powder can be used in small proportions as a Cutting Agent for Cocaine HCL or Methamphetamine (Crystal Meth). It has an almost identical appearance when in powder form and portrays similar qualities when heated. This, in addition to the fact that it adds almost no discernable taste or feel to either drug regardless the method of use, makes it an ideal cutting agent. Cutting either drug at any point in the distribution increases volume of the street product and increases dealer profits. However, at higher cut levels the inositol becomes somewhat noticeable in that the quality of the product is obviously diminished.
#Palatnik, Alex, et. al., "Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder." ''J Clin Psychopharmacol.'' 2001 Jun; 21(3): 335-9.
Abstract
#Fux, M., et. al., "Inositol treatment of obsessive-compulsive disorder." ''The American Journal of Psychiatry.'' v. 153 (September 1996), p. 1219-21.
Abstract
