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Information Hyperlinked Over Proteins




Information Hyperlinked over Proteins (or '''iHOP''') is an online service that provides a gene-guided network to access PubMed abstracts. By using Gene s and Protein s as Hyperlink s between sentences and abstracts, the information in PubMed can be converted into one navigable resource.
Navigating across interrelated sentences within this network rather than the use of conventional keyword searches allows for stepwise and controlled acquisition of information. Moreover, this literature network can be superimposed upon experimental interaction data to facilitate the simultaneous analysis of novel and existing knowledge. The network presented in iHOP currently contains 5 million sentences and 40000 genes from '' Homo Sapien s'', '' Mus Musculus '', '' Drosophila Melanogaster '', '' Caenorhabditis Elegans '', '' Danio Rerio '', '' Arabidopsis Thaliana '', '' Saccharomyces Cerevisiae '' and '' Escherichia Coli ''.

The system was published in ''Nature Genetics'' 36, 664 (2004) as 'A gene network for navigating the literature'.


SOURCE

  • Hoffmann R, Valencia A (2004) A gene network for navigating the literature ''Nature Genetics'' 36(7): 664 PMID 15226743



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