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  Name International Statistical Classification of Diseases and Related Health Problems Codes
  ICD10 B20-B24
  ICD9 -


Human immunodeficiency virus (commonly known as '''HIV''', and formerly known as '''HTLV-III''' and '''lymphadenopathy-associated virus''') is a Retrovirus that primarily infects vital components of the Human Immune System such as CD4+ T Cells , Macrophages and Dendritic Cells . It also directly and indirectly destroys CD4+ T cells. As CD4+ T cells are required for the proper functioning of the immune system, when enough CD4+ T cells have been destroyed by HIV, the immune system functions poorly, leading to the syndrome known as AIDS . HIV also directly attacks Organs , such as the Kidney s, the Heart and the Brain leading to Acute Renal Failure , Cardiomyopathy , Dementia and Encephalopathy . Many of the problems faced by people infected with HIV result from failure of the immune system to protect from Opportunistic Infection s and Cancer s.

HIV is transmitted through direct contact of a or Vaginal ) Sex ; Oral Sex ; Blood Transfusion ; contaminated needles; exchange between mother and infant during Pregnancy , Childbirth , or Breastfeeding ; or other exposure to one of the above bodily fluids.

AIDS is thought to have originated in Sub-Saharan Africa during the Twentieth Century


INTRODUCTION

In 1983 , scientists led by Luc Montagnier at the Pasteur Institute in France first discovered the virus that causes AIDS.

HIV is a member of the genus Lentivirus ,

Two species of HIV infect humans: HIV-1 and HIV-2. HIV-1 is the more virulent and easily transmitted, and is the source of the majority of HIV infections throughout the world; HIV-2 is largely confined to west Africa.

  Author Curtis, T
  Title The origin of AIDS
  Journal Rolling Stone year=1992 pages=54-59, 61, 106, 108 volume= issue=626 url=http://wwwuoweduau/arts/sts/bmartin/dissent/documents/AIDS/Curtis92html


  Author Hooper, E
  Year 1999
  Title The River : A Journey to the Source of HIV and AIDS
  Edition 1st
  Pages 1-1070
  Publisher Little Brown & Co
  Location Boston, MA
  Id ISBN 0316372617




TRANSMISSION

  Style "width: 100px"'''Exposure Route'''
  Style "width: 150px"'''Estimated infections per 10,000 exposures to an infected source'''
  Cite Journal Author Donegan, E, Stuart, M, Niland, J C, Sacks, H S, Azen, S P, Dietrich, S L, Faucett, C, Fletcher, M A, Kleinman, S H, Operskalski, E A, et al title=Infection with human immunodeficiency virus type 1 (HIV-1) among recipients of antibody-positive blood donations journal=Ann Intern Med year=1990 pages=733-739 volume=113 issue=10


  Cite Journal Author Coovadia, H title=Antiretroviral agents&mdashhow best to protect infants from HIV and save their mothers from AIDS journal=N Engl J Med year=2004 pages=289-292 volume=351 issue=3 id=


  Cite Journal Author Kaplan, E H and Heimer, R title=HIV incidence among New Haven needle exchange participants: updated estimates from syringe tracking and testing data journal=J Acquir Immune Defic Syndr Hum Retrovirol year=1995 pages=175-176 volume=10 issue=2


  Cite Journal Author European Study Group on Heterosexual Transmission of HIV title=Comparison of female to male and male to female transmission of HIV in 563 stable couples journal=BMJ year=1992 pages=809-813 volume=304 issue=6830 id=


  Cite Journal Author Varghese, B, Maher, J E, Peterman, T A, Branson, B M and Steketee, R W title=Reducing the risk of sexual HIV transmission: quantifying the per-act risk for HIV on the basis of choice of partner, sex act, and condom use journal=Sex Transm Dis year=2002 pages=38-43 volume=29 issue=1 id=


  Cite Journal Author Bell, D M title=Occupational risk of human immunodeficiency virus infection in healthcare workers: an overview journal=Am J Med year=1997 pages=9-15 volume=102 issue=5B id=


  Cite Journal Author European Study Group on Heterosexual Transmission of HIV title=Comparison of female to male and male to female transmission of HIV in 563 stable couples journal=BMJ year=1992 pages=809-813 volume=304 issue=6830 id=


  Cite Journal Author Varghese, B, Maher, J E, Peterman, T A, Branson, B M and Steketee, R W title=Reducing the risk of sexual HIV transmission: quantifying the per-act risk for HIV on the basis of choice of partner, sex act, and condom use journal=Sex Transm Dis year=2002 pages=38-43 volume=29 issue=1 id=


  Cite Journal Author Leynaert, B, Downs, A M and de Vincenzi, I title=Heterosexual transmission of human immunodeficiency virus: variability of infectivity throughout the course of infection European Study Group on Heterosexual Transmission of HIV journal=Am J Epidemiol year=1998 pages=88-96 volume=148 issue=1 id=


  Cite Journal Author European Study Group on Heterosexual Transmission of HIV title=Comparison of female to male and male to female transmission of HIV in 563 stable couples journal=BMJ year=1992 pages=809-813 volume=304 issue=6830 id=


  Cite Journal Author Varghese, B, Maher, J E, Peterman, T A, Branson, B M and Steketee, R W title=Reducing the risk of sexual HIV transmission: quantifying the per-act risk for HIV on the basis of choice of partner, sex act, and condom use journal=Sex Transm Dis year=2002 pages=38-43 volume=29 issue=1 id=


  Cite Journal Author European Study Group on Heterosexual Transmission of HIV title=Comparison of female to male and male to female transmission of HIV in 563 stable couples journal=BMJ year=1992 pages=809-813 volume=304 issue=6830 id=


  Cite Journal Author Varghese, B, Maher, J E, Peterman, T A, Branson, B M and Steketee, R W title=Reducing the risk of sexual HIV transmission: quantifying the per-act risk for HIV on the basis of choice of partner, sex act, and condom use journal=Sex Transm Dis year=2002 pages=38-43 volume=29 issue=1 id=


  Cite Journal Author Varghese, B, Maher, J E, Peterman, T A, Branson, B M and Steketee, R W title=Reducing the risk of sexual HIV transmission: quantifying the per-act risk for HIV on the basis of choice of partner, sex act, and condom use journal=Sex Transm Dis year=2002 pages=38-43 volume=29 issue=1 id=


  Cite Journal Author Varghese, B, Maher, J E, Peterman, T A, Branson, B M and Steketee, R W title=Reducing the risk of sexual HIV transmission: quantifying the per-act risk for HIV on the basis of choice of partner, sex act, and condom use journal=Sex Transm Dis year=2002 pages=38-43 volume=29 issue=1 id=


  - Bgcolor "#efefef"
  ! Colspan 5 style="border-right:0px" <sup></sup> assuming no condom use </br> <sup>§</sup> Source refers to oral intercourse performed on a man


  Cite Journal Author Coovadia, H journal=N Engl J Med year=2004 pages=289-292 volume=351 issue=3 id=


  Cite Journal Author Coovadia, H journal=N Engl J Med year=2004 pages=289-292 volume=351 issue=3 id=


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  Author Duesberg, P H
  Title HIV is not the cause of AIDS
  Journal Science year=1988 pages=514, 517 volume=241 issue=4865


  Author Papadopulos-Eleopulos, E, Turner, V F, Papadimitriou, J, Page, B, Causer, D, Alfonso, H, Mhlongo, S, Miller, T, Maniotis, A and Fiala, C
  Title A critique of the Montagnier evidence for the HIV/AIDS hypothesis
  Journal Med Hypotheses year=2004 pages=597-601 volume=63 issue=4


  Author Cohen, J
  Title The Duesberg phenomenon
  Journal Science year=1994 pages=1642-1644 volume=266 issue=5191
  Url http://wwwsciencemagorg/feature/data/cohen/266-5191-1642apdf