Haloform Reaction Website Links For
Reaction
 

Information About

Haloform Reaction





USES


The reaction has three application area:



EXAMPLE REACTIONS


The reaction for example, with Chlorine :

:(1) R-CO-CH3 + 3 Cl2 + 3 OH → R-CO-CCl3 + 3 Cl + 3 H2O

:(2) R-CO-CCl3 + OHRCOOH + CCl3

:(3) RCOOH + CCl3RCOO + CHCl3

The reaction for example, with Hypobromite :

Haloforms can also be prepared directly from any secondary alcohol containing the CH3-CHOH- group (such as Isopropyl Alcohol ), since this is oxidised under the reaction conditions to the corresponding methyl ketone, which can then undergo the haloform reaction.

With Chlorine , it is possible to use Sodium Hypochlorite as a convenient source of both base and chlorine. Fluoroform (CHF3) may not be prepared from a methyl ketone by this reaction, but compounds of the type RCOCF3 do cleave with base to produce CHF3; this is equivalent to the second and third steps in the process shown above. The Iodoform Test is a laboratory test for the presence of a methyl ketone or the related alcohol, by formation of a pale yellow precipitate of iodoform.


SEE ALSO




REFERENCES


  • Chakrabartty, in Trahanovsky, ''Oxidation in Organic Chemistry'', pp 343-370, Academic Press, New York, 1978.