Grimes may also refer to:
- Burleigh Grimes (1893 - 1985), US baseball player
- Henry Grimes (1935 - ), US jazz musician
- James W. Grimes (1816 – 1872), US politician
- Ken Grimes (1947 - ), US artist
- Paul Grimes , a former Liverpudlian criminal
- Roger Grimes (1950 - ), Canadian politician
- Scott Grimes (1971 - ), US actor
- W. F. Grimes , British archaeologist
- Grimes Graves , Neolithic flint mining complex in England
- Frank Grimes , Simpsons character
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