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George A. Ricaurte





THE MDMA NEUROTOXICITY CONTROVERSY

''Main article:'' Retracted Article On Neurotoxicity Of Ecstasy

In September 2002 Dr. Ricaurte, together with Jie Yuan, George Hatzidimitriou, Branden J. Cord and Ricaurte's wife Una D. McCann, published the article ''Severe Dopaminergic Neurotoxicity in Primates After a Common Recreational Dose Regimen of MDMA'' in Science . The paper immediately came under criticism from a number of sources. The criticism ranged from the method of administration of the drug Injection , the fact that the study was funded by the National Institute On Drug Abuse , the dosages involved and the 20% mortality rate of the animals used in the study. Almost exactly one year later, the paper was retracted with the explanation that the drug used in study had mistakenly been Methamphetamine and not MDMA, resulting in a 50-fold overdose of Methamphetamine compared to a common recreational dose of MDMA. Dr. Ricaurte claimed that the mixup was the result of mislabeling on behalf of the company that had supplied the drug, Research Triangle Institute —however the matter was not further pursued.


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