Esterase

LIST OF ESTERASES

Lipase , splits Fat and Lipid s into Fatty Acid s and Glycerol or other alcohols

--- Phospholipase (PL), hydrolyzes Phospholipid s

--- Lipoprotein Lipase , hydrolyzes Lipid s in Lipoproteins

--- Acid Hydrolase (lysosomal acid lipase), found in Lysozome s which are strongly acidic

Acetylesterase , splits off Acetyl Groups

--- Cholinesterase

-- Acetylcholinesterase, inactivates the Neurotransmitter Acetylcholine

-- Pseudocholinesterase, broad substrate specificity, found in the Blood Plasma and in the Liver

Nuclease , cleave the phosphodiester bonds between the Nucleotide s of Nucleic Acid s

--- Endonuclease , cleaves in the middle of the nucleic acid

--- Exonuclease , cleaves in the ends of the nucleic acid

--- Ribonuclease (RNase), cleaves RNA

-- RNase H

--- Deoxyribonuclease (DNase), cleaves RNA

-- Restriction Enzyme

Phosphatase , hydrolyses Phosphoric Acid Monoesters into a Phosphate ion and an alcohol

--- Alkaline Phosphatase , removes phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids.

--- Phosphodiesterase (PDE), inactivates the Second Messenger CAMP

-- CGMP Specific Phosphodiesterase Type 5 , is inhibited by Sildenafil (Viagra)

Fructose Bisphosphatase , converts fructose-1,6-bisphosphate to fructose-6-phosphate in Gluconeogenesis

Thioesterase

--- Ubiquitin Carboxy-terminal Hydrolase L1

Cholesterol Esterase

Pectinesterase , clarifies fruit juices

Leukocyte Esterase

Hemagglutininesterase

EC CLASSIFICATION

Esterases are classified as EC 3.1 in the EC Number classification of enzymes. They are further subclassified into:

''EC 3.1.1'': Carboxylic ester hydrolases

''EC 3.1.2'': Thiolester hydrolases

''EC 3.1.3'': Phosphoric monoester hydrolases

''EC 3.1.4'': Phosphoric diester hydrolases

''EC 3.1.5'': Triphosphoric monoester hydrolases

''EC 3.1.6'': Sulfuric ester hydrolases (sulfatases)

''EC 3.1.7'': Diphosphoric monoester hydrolases

''EC 3.1.8'': Phosphoric triester hydrolases

''EC 3.1.11'': Exodeoxyribonucleases producing 5'-phosphomonoesters

''EC 3.1.13'': Exoribonucleases producing 5'-phosphomonoesters

''EC 3.1.14'': Exoribonucleases producing 3'-phosphomonoesters

''EC 3.1.15'': Exonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

''EC 3.1.16'': Exonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters

''EC 3.1.21'': Endodeoxyribonucleases producing 5'-phosphomonoesters

''EC 3.1.22'': Endodeoxyribonucleases producing 3'-phosphomonoesters

''EC 3.1.23'': Site specific endodeoxyribonucleases: cleavage is sequence specific (discontinued)

''EC 3.1.24'': Site specific endodeoxyribonucleases: cleavage is not sequence specific (discontinued)

''EC 3.1.25'': Site-specific endodeoxyribonucleases specific for altered bases

''EC 3.1.26'': Endoribonucleases producing 5'-phosphomonoesters

''EC 3.1.27'': Endoribonucleases producing 3'-phosphomonoesters

''EC 3.1.30'': Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

''EC 3.1.31'': Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters

EXTERNAL LINKS

Enzyme nomenclature

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Information About

Esterase