Information AboutEnhancer |
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An enhancer does not need to bind close to the Transcription initiation site to affect its transcription, as some have been found to bind several hundred thousand Base Pairs upstream or downstream of the start site. Enhancers can also be found within Intron s. An enhancer's orientation may even be reversed without affecting its function. Furthermore, an enhancer may be excised and inserted elsewhere in the chromosome, and still affect gene transcription.That is the reason that intron polymorphisms are checked though they are not transcribed and translated. Currently, there are two different theories on the information processing that occurs on enhancers:
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