Information About

Cholestasis

ETIOLOGY

Gallstone s

Abdominal Mass (e.g. Cancer )

Primary Sclerosing Cholangitis , secondary to Inflammatory Bowel Disease

Primary Biliary Cirrhosis , secondary to autoimmune disorders

congential anomalies of the bilary tract

biliary Trauma

some drugs, (e.g. Flucloxacillin and Erythromycin )

in children, Biliary Atresia and other pediatric liver diseases

SYMPTOMS

Pale stools,

dark urine,

itchiness ( Pruritus ) and

Jaundice .

Bile is secreted by the liver to aid in the Digestion of Fats . Drugs such as Gold Salts , Nitrofurantoin , Anabolic Steroids , chlorpromazine, prochlorperazine, sulindac, cimetidine, Erythromycin , can cause cholestasis and may result in damage to the Liver .

SEE ALSO

Liver Function Tests

Lipoprotein-X - an abnormal Low Density Lipoprotein found in cholestasis

EXTERNAL LINKS

Drug-induced cholestasis - medlineplus.org

Cholestasis - emedicine.com

Liver Families = pediatric liver support group