:
- Zeno (emperor) (c.425–491), Emperor of the Eastern Roman Empire 474–491
- Zeno Of Citium (333–264 BC), Hellenistic philosopher of the Painted Porch, founder of Stoicism
- Zeno Of Elea (c.490–c.430 BC), Hellenic Eleatic philosopher, follower of Parmenides and famous for his paradoxes
- Zeno Of Sidon (first century BC), Epicurean philosopher
- Zeno Of Tarsus (third century BC), Middle Stoa philosopher
- Zeno Of Verona (c.300–c.380), Roman Catholic Saint and an early Christian Bishop or martyr
- The Zeno Brothers (fourteenth century), Antonio, Carlo, and Nicolò Zeno, Venetian navigators
- Nicolò Zeno (younger) , publisher of the Zeno Map
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