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The genome of viruses can be a RNA and/or a DNA , double stranded or single stranded, positive-sense or negative-sense, circular or linear, segmented or continuous. Depending on the intrinsic nature of the genome and a number of factors, different viruses employ different strategies to amplify their genome. David Baltimore , a Nobel Prize -winning biologist, devised a system called the Baltimore Classification System to classify different viruses based on their unique replication strategy. There are seven different replication strategies based on this system (Baltimore Class I, II, III, IV, V, VI, VII).